Purpose
La cheratite infettiva è una condizione oftalmica comune nei pazienti canini e felini. I fattori di rischio per il fallimento del trattamento dopo cromoforo fotoattivato per cheratite – cross-linking corneale (PACK-CXL) in pazienti canini e felini non sono ben definiti.
Results
- Overall success PACK-CXL treatment: 90% (95%CI: 88-92%).
- PACK-CXL treatment acceleration is the only investigated variable directly associated with treatment outcome (ABN).
- Dogs receiving eye drop therapy + PACK-CXL epithelialize faster than dogs receiving PACK-CXL only (Kaplan-Meier
survival analysis: figure 2). - A history of pre-existing ocular disease or previous ocular surgery, hypopyon or a larger ulcer size at presentation delay epithelization (Cox proportional hazard regression analysis).
Conclusions
- PACK-CXL is a highly successful adjunctive treatment for the management of infectious keratitis in dogs and cats.
- Canine patients may benefit from accelerated PACK-CXL; the reasons for this apparent positive impact on treatment outcome remain unclear.